中国驱动基因阳性非小细胞肺癌脑转移诊疗指南(2025版)

标题: 中国驱动基因阳性非小细胞肺癌脑转移诊疗指南(2025版)
title: Chinese Guidelines for Managing Brain Metastases in Non-Small Cell Lung Cancer with Actionable Driver Mutation (2025 Edition)
版本: 原创版
version: Original
分类: 标准指南
classification: Standard guideline
领域: 综合
field: Comprehensive guideline
国家和地区: 中国
Country and region: China
指南使用者: 胸部肿瘤医生
Guide users: Throacic oncologist
证据分级方法: GRADE分级
Evidence grading method: GRADE
制定单位: 中国医药教育协会肺癌医学教育委员会
Formulating unit: Lung Cancer Medical Education Committee of Chinese Medicine Education Association
注册时间: 2024-05-09
Registration time:
注册编号: PREPARE-2024CN635
Registration number:
指南制订的目的: 原发性肺癌(以下简称肺癌)是中国发病率和死亡率最高的恶性肿瘤,致死率位居我国恶性肿瘤发病首位。由于肺脏血运丰富,肺癌常见远处转移,脑部是常见远处转移之一。 肺癌脑转移患者预后差,自然平均生存时间仅为1~2个月。外科手术、放射治疗技术和内科治疗的迅速发展为肺癌脑转移患者提供了越来越多的治疗选择,中国Ⅳ期原发性肺癌的治疗水平在不断提高,改善了肺癌脑转移患者的生活质量、延长了生存时间。 为了进一步规范我国肺癌脑转移患者的治疗,由支修益教授和王洁教授牵头制定了《中国驱动基因阳性非小细胞肺癌脑转移诊疗指南(2025版)》,以期全面改善肺癌脑转移患者的生存预后。
Purpose of the guideline: Primary lung cancer, which leads in both incidence and mortality rates among all malignant tumors in China, ranks first in fatalities caused by malignant diseases. Given the lung's rich blood supply, distant metastases of lung cancer are common, with the brain being a frequent site for such metastasis. Patients with brain metastases from lung cancer have a poor prognosis, with a natural median survival time of only 1 to 2 months. However, the rapid development of surgical procedures, radiotherapy techniques, and medical treatments has increasingly diversified treatment options for these patients. The treatment level for stage IV primary lung cancer in China has been continuously improving, enhancing the quality of life and extending the survival time for patients with brain metastases from lung cancer. To further standardize the treatment of patients with brain metastases from lung cancer in China, Professors Zhi-Xiu Yi and Jie Wang have spearheaded the development of the "Chinese Guidelines for Managing Brain Metastases in Non-Small Cell Lung Cancer with Actionable Driver Mutation (2025 Edition) " aiming to comprehensively improve the survival prognosis of these patients.